| Synthesis of C6-substituted uridine-5'-monophosphate derivatives as potential inhibitors of orotidine-5'-monophosphate decarboxylase |
2009 |
5169 |
Orotidine-5'-monophosphate decarboxylase (ODCase) is an enzyme that catalyzes the final step during the de novo synthesis of uridine-5'-monophosphate (UMP). Several UMP derivatives modified at the C6 position, including 6-iodouridine-5'-monophosphate... |